"Can't never could do nothin'!" - A Southernism, normally used by parents/authority figures when they've asked someone (usually a kid) to do something and that person doesn't want to do it or to even try it and replies with "I can't!" Often the can't rhymes with "ain't".
More Southernisms: "Slicker than snot on a doorknob." "The sun don't always shine on the same dog's @ss!" "That don't cut no mustard with me!" "As crooked as a dog's hind leg"
Reading a 1960s text containing the phrase "handsome slob of man" made me laugh about the good old days. Surprisingly absent from the omniscient internet. I guess it was a way to say someone was good looking without sounding gay. Although I recall an odd line in a THE INVADERS episode where a detective was describing someone and added "you might call him handsome" (which is subjective, not an objectively identifiable marking).