I was surprised he was 50, though 50 is too damn young to go.
He genuinely seemed like a nice guy and was a highlight in that recent DS9 documentary. His character might have the biggest story arc in the franchise, considering what the writers put him through by Season 7.
Nog was annoying to me when he first appeared, but the story they created for him throughout the series was really good and he - the character and the actor - totally won me over.
My wife and I loved him in DS9, heck, we loved all the Ferengis (and before I did a full series watch a few years ago I didn't think I'd ever say that). Very sad to hear this, but wonderful to see all the love from Trek colleagues.